IndraLab

Statements

USP25 inhibits Ubiquitin. 4 / 4
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"Overexpression of USP21 significantly reduced ubiquitin incorporation into MARK1 but has less impact on the MARK1K768A mutant (XREF_SUPPLEMENTARY)."
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"USP21 inhibits antiviral response independent of A20 ubiquitin editing complex."
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"For example, it is associated with endoplasmic reticulum-associated degradation , and acute endoplasmic reticulum (ER) stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation by USP25 ."
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"Accordingly, incubation with USP21 abrogated the Ub smearing pattern, leading to the appearance of oligomeric, as well as monomeric forms of MLKL (Fig. 2f)."
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