IndraLab

Statements

Ubiquitin activates UCHL1. 4 / 5
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"Indeed, the addition of 1.2 molar equivalent of ubiquitin slightly increased the thermal stability of UCH-L1 and -L3, raising the melting temperature by 2.2 +/-0.1 degreesC and 0.9 +/-0.2 degreesC, respectively, while no significant change in thermal stability was observed for UCH-L5 N240 (XREF_SUPPLEMENTARY)."
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"For example, Ubiquitin carboxy-terminal hydrolase L1 antisense RNA 1 (UCHL1-AS1) interacts with polysomes and thus promotes the translation of UCHL1 mRNA."
30018955
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"In the nucleus of dopaminergic neurons, the lncRNA ubiquitin carboxy-terminal hydrolase L1 (UCHL1) antisense transcript causes increased UCHL1."
39199508
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"It remains to be established how and whether the ubiquitin modulating functions of PGP9.5 observed in neuronal cells translate into a functional role of the protein in naphthalene exposed lung epithelium."
18687389