IndraLab

Statements

HSPA activates ATXN3. 3 / 3
| 3
reach
"It was previously reported that overexpression of CHIP increases the ubiquitination and degradation rates of polyQ expanded Atx3, which is also enhanced by HSP70 XREF_BIBR."
21625540
reach
"Another example of the gene-to-drug transition is the rescue of Atx3 and alpha-Syn toxicity by Hsp70."
22288402
reach
"The increased turnover of both ataxin-3 variants induced by Hsp70 and the large number of Hsp70 family chaperones in the MS analysis suggests that a subpopulation of ataxin-3 adopts a non native confo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29111377