IndraLab

Statements

NAC inhibits STAT1. 4 / 4
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"In a similar fashion, V 2 O 5 -stimulated STAT1 signaling is also attenuated by catalase or NAC."
19994902
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"Alternatively, NAC may directly inhibit pSTAT-1 and T-bet activation independent of IFN-gamma."
22701598
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"Since we showed that treatment with the ROS scavengers, tiron, NAC and mitoTEMPO strongly reduced STAT1 activation, it suggested that oxidative damage to mtDNA and subsequent generation of DNA fragments and their eventual leakage into the cytosol may be responsible for the observed increase in STAT1 phosphorylation in PNKP-depleted cells."
39087523
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"Interestingly, even in the stimulated condition, NAC treatment reduced the ratio of phospho-STAT1 and total STAT1 in NNS patient derived MT-MLs (XREF_FIG B)."
29731430