IndraLab

Statements

OTUD3 binds HNF1B. 3 / 3
1 | 2
sparser
"More importantly, unlike the WT form, the 4CS mutant HNF1B could not be succinated by DMF (Fig. xref ), and DMF impaired the interaction between OTUD3 and WT HNF1B, while there was no detectable change in the interaction between OTUD3 and 4CS mutant HNF1B upon DMF treatment (Fig. xref )."
39915461
biogrid
No evidence text available
35675826
sparser
"Collectively, these data suggest that OTUD3 binds to and stabilizes HNF1B, and that DMF treatment impairs this interaction, thereby promoting the degradation of HNF1B via ubiquitin-proteasome pathway."
39915461