IndraLab

Statements

Hydroxychloroquine activates cyclophosphamide hydrate. 5 / 5
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"Additionally, 92.1% of the patients were treated with immunosuppressants, among which 58.2% were treated with cyclophosphamide (CYC), 70.1% were treated with hydroxychloroquine (HCQ) and 41.4% were treated with more than two immunosuppressants."
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"During follow-up, immunosuppressive management consisted of azathioprine in 54%, cyclophosphamide in 66.6%, mycophenolate mofetil in 31%, a combination of more than one of the above in 56.7%, being the most frequent azathioprine and cyclophosphamide; 22 individuals (14%) were only treated with hydroxychloroquine as an immunomodulator."
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"For immunosuppressors, 67.6% SLE-PAH patients were treated with cyclophosphamide, and 47.7% were treated with hydroxychloroquine."
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"XREF_BIBR, XREF_BIBR Chloroquine and hydroxychloroquine can inhibit autophagy induced by p53 controlled apoptosis in Myc driven lymphoma and augmented the anticancer activity of cyclophosphamide."
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"Two antimalarial drugs, CLQ and hydroxychloroquine, inhibited the autophagy induced by p53 mediated apoptosis and augmented the anticancer activity of cyclophosphamide in Myc driven lymphoma [XREF_BIBR, XREF_BIBR]."
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