IndraLab

Statements


USP8 ubiquitinates PRKN. 3 / 3
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sparser
"Utilizing a mutant ubiquitin only capable of K6-linked conjugates, we observed the expected reduction of K6-linked Parkin ubiquitination by USP8 ( xref )."

reach
"USP8, instead, antagonizes mitophagy by directly deubiquitinating PARKIN, so contributing to its recruitment and activity."

reach
"Here, we reported the important ubiquitination markers, including the E3 ligases- PARK2, STUB1, FBXW7 SIAH1, FBXO7, WDTC1, SYVN1, TRAF6, RNF19A, SIAH2, TRIM32, NEDD4, FBXL2, MARCH7, and FBXO45, and th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"