IndraLab

Statements

USP8 leads to the ubiquitination of PRKN. 2 / 2

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sparser

"Utilizing a mutant ubiquitin only capable of K6-linked conjugates, we observed the expected reduction of K6-linked Parkin ubiquitination by USP8 ( xref )."

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reach

"USP8, instead, antagonizes mitophagy by directly deubiquitinating PARKIN, so contributing to its recruitment and activity."

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INDRA sources:

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IndraLab

Statements

USP8 leads to the ubiquitination of PRKN. 2 / 2

INDRA sources:

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