IndraLab

Statements

USP12 activates Neoplasm Invasiveness. 4 / 4
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"Moreover, overexpressing USP12 in gastric cancer cell lines enhanced cell migration and invasion, while overexpression of USP12 did not (Fig. 3D, E)."
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"Therefore, the mechanism of action of USP12 on apoptosis and autophagy merits more investigation to develop novel insight into therapeutic strategies.Besides the above, USP12 has also been proven to mediate cancer invasion and metastasis."
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"Moreover, the transwell assay showed that overexpression of YAP partially restored the cell migration and invasion suppressed by USP12 deletion (Fig. 5E, F)."
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"Additionally, the transwell assay revealed that USP12 deletion decreased cell invasion and migration (Fig. 2D–G)."
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