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Phosphatidylinositol activates KCNMA1. 4 / 4
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"Inhibition of phosphatidylinositol 4-phosphate (PI4P) and phosphatidylinositol 4,5-bisphosphate (PI4,5 P (2)) synthesis by phenylarsine oxide (PAO) inhibits both [3H]-noradrenaline ([3H]-NA) and [14C]-glutamate ([14C]-glu) exocytosis from streptolysin-O (SLO)-perforated synaptosomes."
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"However, in contrast to the present study, a PI 3-kinase driven process mediates actin filament disruption and BK channel activation by leptin."
17618127
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"In parallel with the actions of leptin on K ATP channels (Harvey et al., 2000b), the ability of leptin to modulate BK channel activity requires stimulation of a PI 3-kinase-driven process (Shanley et [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We next examined whether the specific structure of the headgroup contributes to phosphoinositide action on the BK channel by probing PI vs. 1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (PS)."
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