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Statements


AKT leads to the deubiquitination of USP22. 2 / 2
| 2

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"Loss of AKT-mediated phosphorylation markedly increased USP22 ubiquitination and abolished EPI-induced inhibitory efficacy (Fig. 6D)."

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"As a consequence, overexpression of AKT markedly inhibited USP22 ubiquitination and prolonged its half-life (Fig. 5, H to J)."