IndraLab

Statements


Hydrogen-Ion Concentration leads to the deubiquitination of USP28. 2 / 2
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"Chronic stress induced epinephrine activated LDHA to generate lactate, and the adjusted pH directed USP28 mediated deubiquitination and stabilization of MYC."

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"This leads to a switch to lactate production, and the adjusted pH then directs USP28 mediated deubiquitination and stabilization of MYC, thereby promoting stem like traits in breast cancer."