IndraLab

Statements

USP36 deubiquitinates PARP1. 2 / 2

| 2

reach

"As shown in Fig. 4 A , overexpression of USP36 WT promoted the deubiquitination of PARP1 and increased the levels of PARP1 in HEK293T cells, while the C131A mutant failed to induce PARP1 level."

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➶

reach

"This investigation provides compelling evidence that USP36 deubiquitinates PARP1, suggesting that the USP36/PARP1 axis is a promising therapeutic target for Dox-induced cardiomyopathy [63] (Figure 2G)."

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IndraLab

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USP36 deubiquitinates PARP1. 2 / 2

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