IndraLab

Statements

ATXN3 inhibits CHEK1. 3 / 7
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"Expression of FBXO6 induced higher level of polyubiquitination in Chk1, which can be remarkably decreased by co-expression of ATX3."
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"ATX3 deficiency impairs Chk1 mediated G2/M DNA damage checkpoint."
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"To test if ATX3 may promote Chk1 stabilization, we first evaluated whether ATX3 deficiency impairs Chk1 stability."
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