IndraLab

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TnT3 inhibits CACNA1S. 2 / 2

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"TnT3 downregulation or overexpression decreased or increased, respectively, Cacna1s promoter activity, and the effect was ablated by truncating the TnT3 nuclear localization sequence."

26892246

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reach

"These results indicate that (i) TnT3 enhances Cacna1s promoter activity, (ii) TnT3 knockdown directly reduces Cacna1s promoter activity in skeletal muscle, and (iii) preventing TnT3 's nuclear translocation inhibits its effect on Cacna1s transcription."

26892246

INDRA sources:

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IndraLab

Statements

TnT3 inhibits CACNA1S. 2 / 2

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