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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified TP53 activates TP53-R172H. 1 / 1

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"As shown in XREF_FIG, expression of mutp53 greatly increased the levels of RhoA-GTP but not the total RhoA in H1299 and p53 R172H and R172H MEF cells, and furthermore, knockdown of endogenous mutp53 greatly reduced the levels of RhoA-GTP but not the total RhoA in MDA-MB468 and SK-BR3 cells."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...