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USP2 activates TP53. 2 / 2

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"On the other hand , USP2 has also been shown to increase p53 in a hepatoma cell line ( HepG2 ) and a breast cancer cell line ( MCF7 ) after leptin stimulation [ 36 ] ."

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"USP2a mediated enhanced stability of MDM2 abrogates p53 accumulation and its tumor suppressive functions."

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IndraLab

Statements

USP2 activates TP53. 2 / 2

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