IndraLab
Statements
reach
"Consistently, overexpression of wild type (WT), but not the catalytic-inactive (CA) mutant of USP13 with a mutation at the core enzymatic domain, could rescue the decreased nsp13 levels caused by USP13 depletion, suggesting that USP13 can regulate nsp13 levels most likely by deubiquitinating and consequently stabilizing nsp13."