IndraLab

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Prazosin inhibits FOS. 2 / 2
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"Prazosin reduced FCL (SD)-induced elevations of c-jun and c-fos, but not NGFI-A, mRNA."

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"In confirmation, marked c-fos responses that were blocked by an alpha (1)-antagonist (prazosin) were found in four of these brain regions (secondary motor, cingulate, piriform cortices, and nucleus accumbens) of animals exposed to a mildly novel environment (clean cage), which elicits a high degree of sustained exploratory activity."