IndraLab

Statements


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"In our study, isoflurane significantly decreased NADH, furthermore, over-expression of TREK1 also significantly decreased NADH, which further indicated that isoflurane induced neuroprotection by up-regulation of TREK1."

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"The over-expression of TREK-1 contributed to isoflurane induced astrocytic cytotoxicity."

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"TREK-1 pathway mediates isoflurane induced memory impairment in middle aged mice."

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"Furthermore, the mRNA and protein expression of TREK-1 increased significantly in the 1.0 MAC (P < 0.05) and 1.5 MAC (P < 0.01) isoflurane treated groups."

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"TREK-1 mediates isoflurane induced cytotoxicity in astrocytes."