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Selenium atom inhibits STING1. 3 / 3
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"In addition to gut, STING1 also participates in heart tissue apoptosis.104 During sepsis, LPS-induced STING1 upregulation contributes to apoptosis and subsequent heart injuries in mice, while this process can be inhibited by the administration of selenium, which inactivates the STING1 pathway."
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"In the context of myocardial injury, selenium treatment inactivated STING signaling in mouse heart tissues through an unknown mechanism ( Wang et al., 2021 )."
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"In addition, selenium supplementation inactivated the Sting pathway."
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