IndraLab

Statements

Iron atom inhibits STAT1. 6 / 6
| 6
reach
"Another example of the interconnection between ligand independent endocytosis of IFNGR2 and negative down-modulation of STAT1 activation was given by the finding that iron uptake by the transferrin re[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17493737
reach
"Iron Inhibited STAT1 Pathway in M1 Macrophages."
28286378
reach
"Further, they demonstrated that iron treatment lowered the activity of STAT1, an important transcription factor in pro-inflammatory cytokine production, which suggests a likely mechanism for the attenuation of the M1 response in their model [11]."
35742946
reach
"NF-IL6, HIF-1, and STAT1 are frequently suppressed by cellular iron excess, in stark contrast to NF-B [134–136]."
37946846
reach
"Although the mechanism by which iron withdrawal inhibits STAT1 and STAT3 activation is not yet fully known, it is noteworthy that iron is involved in the inhibition of protein tyrosine phosphatases in macrophages."
37342371
reach
"Conversely, iron supplementation also inhibits M1-like polarization by inhibiting STAT1 activation [38]."
36547083