IndraLab

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USP37 binds CMG. 2 / 2

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"We therefore tested whether the USP37 PH domain is similarly important for USP37 binding to CMG."

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"Through a series of complementary approaches, we discovered that USP37 binds to the replisome, controls the level of polyubiquitin on MCM7 in cells, and prevents premature CMG unloading."

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INDRA sources:

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IndraLab

Statements

USP37 binds CMG. 2 / 2

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