IndraLab

Statements

OTUD6B activates cell population proliferation. 11 / 11
| 11
reach
"Our results revealed that knockdown of OTUD6B significantly impaired the viability, clonal expansion, and proliferation of LUAD cells (Fig. 2C–G)."
38880876
reach
"One study found that OTUD6B drives the G1/S transition and promotes the proliferation of multiple myeloma cells by suppressing microRNA biogenesis via LIN28B stabilization [ 11 ]."
37634410
reach
"Using nude mice and AMC–HN–8 as the representative cell lines, we explored how OTUD6B modulated in vivo proliferation of the tumor cells."
37634410
reach
"In CCA cells, OTUD6B knockdown reduced CCA cell proliferation and promoted apoptosis."
39192576
reach
"In the current study, using AMC–HN–8 and TU177 cells as representative LSCC models, we confirmed that OTUD6B overexpression enhanced the proliferation of LSCC in vitro and in vivo ."
37634410
reach
"In addition, lung cancer cell lines with OTUD6B knockdown significantly inhibited proliferation and invasion ability of lung cancer cells."
36052059
reach
"It is also obvious that OTUD6B silencing inhibited the proliferation, migration, and invasion of A549 and Pc9 cells ( Figures 10C–E )."
36052059
reach
"OTUD6B knockdown inhibited the proliferation of LUAD cells and enhanced apoptosis and inhibited metastasis in LUAD cells suppressed."
38880876
reach
"We found that activation of Otud6b expression with rOtud6b increased endothelial cell inflammation and apoptosis, smooth muscle cells inflammation and proliferation."
38878112
reach
"OTUD6B knockdown inhibited the proliferation of LUAD cells."
38880876
reach
"OTUD6B depletion also led to a G1/S arrest and reduced proliferation in cancer cells of epithelial origin such as A549 lung adenocarcinoma cells, suggesting a more general role of OTUD6B in promoting cell cycle progression (Fig EV2A–C)."
36059274