IndraLab

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"CaM1- and L-VGCC-mediated Ca 2+ signalling pathways were activated by scoparone."

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"In this study, the EC of scoparone for PDE activation by CaM1 was 4.92 μM, suggesting that scoparone could indirectly activate the CaM1 protein in vitro (Fig. 4a-c)."

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"Furthermore , RNAi and electrophysiological data showed that the CaM1 - and L-VGCC-mediated Ca 2 + signalling pathways were activated by scoparone ."