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USP26 activates Neoplasm Metastasis. 7 / 7
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"Therefore, we tested whether USP26 promote metastasis in ESCC cells."
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"And knockdown of USP26 inhibited the lung metastasis of KYSE150 cells ( Fig. 4 F)."
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"Through in vitro and in vivo experiments, we found that depletion of USP26 inhibited breast cancer cell proliferation and invasion, and suppressed tumor growth and metastasis in nude mice."
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"PSMD14, OTUB1, USP26, and EIF3H, by stabilizing Snail, promote the occurrence of metastasis[24-27]."
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"Taken together, these results reveal that USP26 promotes ESCC metastasis through increasing Snail stability and inducing the progress of EMT.To further study the relationship of USP26 and Snail in ESC[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In addition, knockdown of Snail reversed the EMT process and the effect of USP26 overexpression on promoting metastasis of ESCC cells."
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"These observations further proved that USP26 enhanced metastasis of ESCC cells through stabilization of Snail."
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