IndraLab

Statements

FN1 activates KCNMA1. 3 / 3
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"Fibronectin, an alpha5beta1 integrin ligand, enhanced BK channel activity through Ca 2+ and phosphorylation dependent mechanisms in VSMC."
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"Recently, we found that fibronectin, an endogenous alpha5beta1 integrin ligand, enhances BK channel current through both Ca (2+) - and phosphorylation dependent mechanisms in vascular smooth muscle."
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"In an earlier study, native FN was reported to enhance BK channel activity through a Src kinase/tyrosine phosphorylation– dependent mechanism (Yang et al., 2010)."
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