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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PRKN decreases the amount of ATXN3. 2 / 2

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"Parkin lowered the levels of nNOS and Q78 ataxin-3 but did not affect GR or AR112Q, suggesting that it acts redundantly to CHIP on some substrates."

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"Also, consistent with effects in non neuronal cells, both CHIP and Parkin decreased Q78 ataxin-3 levels in MN-1 neuronal cells but Mdm2 did not (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...