IndraLab

Statements



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"In addition, USP2 inhibition suppressed CFs proliferation, collagen synthesis and cell cycle progression."

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"Mutations in the CYLD deubiquitinating enzyme leads to familial cylindromatosis XREF_BIBR and overexpression of USP2 has been reported to increase prostate cancer cell proliferation through the stabilization of fatty acid synthase XREF_BIBR."

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"USP2 promotes cell proliferation and metastasis in choroidal melanoma via stabilizing Snail."

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"USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network."

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"These results suggest that USP-2 promotes cell proliferation pertinent to the features of human hepatic and breast cancers."

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"USP2 overexpression promoted proliferation and metastasis, and induced the EMT in CM cells in vitro, while specific inhibition of USP2 by ML364 produced the opposite effects."