IndraLab

Statements

FOXO6 increases the amount of USP7. 6 / 6
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"Collectively, these data indicated that FOXO6 promoted the proliferation and angiogenesis of EC by mediating USP7 expression via the JMJD3 and CLU pathway."
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"FOXO6 also induced the expression of ubiquitin-specific-processing protease 7 (USP7), leading to an elevation of p53 protein expression levels in A549 cells, which indicate FOXO6/USP7 molecular networ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, silencing of FOXO6 expression attenuated the mRNA and protein levels of USP7, but it enhanced apoptotic protein cleaved-caspase3 (c-CASP3) expression (XREF_FIG C and 3D)."
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"USP7 expression is also enhanced by FOXO6, which inhibits proliferation of lung carcinoma [XREF_BIBR]."
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"In addition, FOXO6 knockdown suppressed the expression of USP7 and that of apoptosis related protein c-CASP3."
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"The above evidence revealed that FOXO6 upregulated the expression of USP7 in EC to inhibit the apoptosis of tumor cells and promote their proliferation."
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