IndraLab

Statements

Matrine inhibits KCNH2. 2 / 2
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"Unlike most other blockers exerting blocking effect at the intracellular sites by entering the cell with the opening of HERG channel, matrine blocked HERG channels at the extracellular sites."
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"Matrine had no significant effect on the activation kinetics, and mainly blocked HERG channels in their closed state."
20535583