IndraLab

Statements

USP5 inhibits RIGI. 3 / 3
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sparser
"Our findings demonstrated that USP5 significantly inhibited RIG-I-, MAVS-, TBK1-, IKKi-, and IRF3-induced IFN-β and ISRE transcription activities ( xref ), suggesting that IRF3 might be the target by which USP5 negatively regulates anti-RNA viral response."
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reach
"Recently, Liu et al. reported that human USP5 inhibited the IFN response by targeting RIG-I for degradation [ 27 ]."
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eidos
"IsoT somewhat reduces the MAVS stimulatory activity of RIG-I ( sample 2 ) , but is still more efficient than RIG-I without RIPLET ( sample 3 ) ."
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