IndraLab

Statements

DUSP binds USP4 and UBL. 4 / 4
| 4
sparser
"By binding to the linker between the DUSP and UBL domain of USP4, SART3 can shuttle USP4 to the nucleus from the cytosol through its NLS."
33681193
sparser
"The crystal structure of USP4 DUSP-UBL shows a dimer formation where the subunits are packed against each other in an antiparallel orientation ( xref ) ( xref )."
33681193
sparser
"Indeed, surface plasmon resonance (SPR) shows an interaction of DUSP–Ubl with immobilized USP4 CD ( xref )."
25404403
sparser
"The binding of USP4 N-terminal DUSP-Ubl domain promotes a change of a switching loop near the active site, and hence enhances ubiquitin dissociation and makes it achieve full catalytic activity xref ."
30478318