IndraLab

Statements

UCHL3 leads to the ubiquitination of FOXM1. 2 / 2
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"Ubiquitin C-terminal hydrolase L3 (UCHL3) as a deubiquitinating enzyme is able to inhibit FOXM1 ubiquitination and degradation 270, while Human leukocyte antigen F-associated transcript 10 (FAT10) as a ubiquitin like protein is able to inhibit FOXM1 ubiquitination and stabilize FOXM1 expression by competing with ubiquitin for binding to FOXM1 271."
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reach
"The down-regulation of UCHL3 and FAT10 increased FOXM1 ubiquitination, and also promoted the sensitivity of PC cells to gemcitabine 270, 271."
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