IndraLab

Statements

Proteasome inhibits USP1. 3 / 3
| 3
reach
"Upon UV DNA damage, USP1 is auto-cleaved and degraded by the proteasome."
22744751
reach
"First, transcription of the USP1 gene is turned off, and second, the USP1 protein present in the cells is quickly degraded by the proteasome, in a process that appears to be initiated by an endo-proteolytic cleavage (possibly autocleavage) at an internal GG motif of USP1."
19686080
reach
"USP1 gets cleaved, and subsequently degraded by the proteasome system in response to UV light exposure, but not to alkylating or cross linking agents [XREF_BIBR, XREF_BIBR]."
20847899