IndraLab

Statements

KCNF1 binds ATR2. 5 / 5
| 1 4
sparser
"In free NusA the AR2 domain binds to the KH1 domain of the SKK motif, preventing RNA binding by NusA-SKK and rendering NusA autoinhibited xref , xref , xref ."
32313022
sparser
"Autoinhibition of NusA is mediated by AR2-KH1 interaction and released by αCTD."
21742261
sparser
"The latter contact induces release of the auto-inhibitory AR2-KH1 interaction, which then allows the S1, KH1 and KH2 domains to also interact with the nascent RNA transcript xref ."
38729929
reach
"This binding releases anauto-inhibitory interaction between AR2 and KH1 and promotes RNA binding to NusA."
29499136
sparser
"In contrast to KH1, resonances from the S1 and KH2 regions were not affected, suggesting that AR2 interacts exclusively with the KH1 domain (Figure xref , xref )."
21742261