IndraLab

Statements

UCHL5 increases the amount of SMAD3. 2 / 2
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"Taken together these data indicate that knockdown of UCH37 strongly inhibits the early phase of Smad3-dependent gene transcription, and that this effect is specific since BMP-regulated Smad1/5 gene tr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Inhibition or down-regulation of UCHL5 reduced Smad2 and Smad3 levels and TGFbeta-1-induced the expression of FN and alpha-SMA in human lung fibroblast."
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