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USP9X leads to the deubiquitination of RNF115. 4 / 4
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"Biochemical evidence further indicated that depletion of USP9X increased, whereas overexpression of USP9X decreased, RNF115 ubiquitination (Figure 5)."

"Conversely, overexpression of <span class="match term0">USP9X</span> resulted in an accumulation of <span class="match term1">RNF115</span> protein, accompanied by a decrease in its ubiquitination"

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"Immunoblotting analysis showed that depletion of USP9X increased the ubiquitination of RNF115 protein (Figure 5E)."

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"Conversely, overexpression of USP9X decreased RNF115 ubiquitination (Figure 5F)."