IndraLab

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"In a myocardial I/R model of diabetic rats, I/R activates ubiquitin-specific protease 19 (USP19) and Beclin1, leading to ferroptosis, while resveratrol can inhibit iron death by downregulating USP19/Beclin1 and upregulating GPX4 and FTH1, thus reducing myocardial cell I/R injury."