IndraLab

Statements

USP25 activates cell population proliferation. 37 / 37
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"The expression of USP21 may promote proliferation, migration and invasion of breast cancer cells."
28105162
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"These data demonstrate that USP21 promotes cell proliferation via its deubiquitinating active site."
33389794
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"USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma."
28223825
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"In non small cell lung cancer, USP21 promotes tumor cell proliferation, migration, and invasion through the YY1 and SNHG16 axis."
33791299
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"USP21 promotes cell proliferation in vitro."
31956270
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"The expression of USP21 promoted DLBCL cell proliferation, while it had no obvious effect on cell death."
33389794
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"Together, our findings demonstrated that USP21 promoted cell proliferation in BC."
28223825
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"USP21 inhibition suppressed AMC-HN-8 and TU686 cell proliferation, migration and invasion."
36919585
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"We reported that USP21 promoted GC cell proliferation, migration, invasion, and stemness in vitro, and regulated GC tumor growth and cell stemness in mice in vivo."
33791299
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"We also showed that USP21 contributed to the progression of tumorigenesis by increasing proliferation, migration, and invasion."
31956270
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"USP21 upregulation in cholangiocarcinoma promotes cell proliferation and migration in a deubiquitinase dependent manner."
33052017
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"XREF_BIBR, XREF_BIBR Recently, one report indicated that USP21 promotes cell proliferation and invasion ability in human renal cell carcinoma."
28223825
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"Thence, in vitro cell experiments were performed and it was found that overexpression of USP21 promoted cell proliferation, migration, invasion, EMT, and stemness, whereas inhibiting its expression posed opposite effects."
33791299
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"A study by Chen et al. reported that USP21 promoted cell proliferation and metastasis in bladder cancer via deubiquitinating EZH2 and stabilizing it."
31956270
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"USP21 inhibition decreases HCC cell proliferation and tumor growth."
29706623
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"These results demonstrate that USP21 promotes cell proliferation by inducing cell cycle progression in HL-7702 and MHCC97L cell lines."
29706623
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"These data revealed that USP21 not only promoted cell proliferation but also facilitated cell migration and invasion in BC."
28223825
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"We identify that knockdown of USP21 inhibits cell proliferation, and overexpression of USP21 promotes cell growth."
33389794
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"In bladder cancer, USP21 is highly expressed and patients with high expression levels have poor survival, and USP21 can accelerate the proliferation and metastasis of bladder cancer cells via inhibiting EZH2 ubiquitination."
33791299
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"USP21 promoted NSCLC cell proliferation, migration, and invasion and in vivo tumor growth by stabilizing a well-known oncogene, Yin Yang-1 (YY1), via mediating its deubiquitination."
31956270
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"Therefore, USP21 stimulates cell proliferation but can not cause cell death."
33389794
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"CCK-8 and EdU immunofluorescent staining assays revealed that USP21 promoted the proliferation of nasopharyngeal carcinoma cells."
36820242
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"USP21 Promotes the Proliferation, Migration, Invasion, and Stemness of GC Cells."
33791299
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"As shown in XREF_FIG, ectopic expression of USP21 obviously increased the proliferation rates of 5637 and T24 cells, whereas the inhibition of USP21 expression significantly inhibited cell proliferation."
28223825
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"We found that overexpression of USP21 dramatically increased cell proliferation, while USP21-CA could not."
33389794
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"USP21 overexpression significantly promoted cell proliferation (Fig. 2c), whereas USP21 silencing inhibited cell proliferation (Fig. 2d)."
31956270
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"USP21 knockdown dramatically decreased cell proliferation rate examined by CCK8 assay."
33389794
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"These results demonstrated that USP21 stimulated cell proliferation, migration, invasion, and stemness of GC cells."
33791299
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"In addition, rescue assays reveal that reintroduction of USP21 wildtype other than the deubiquitinase deficient C221A mutant restores USP21 depletion induced attenuation in cell proliferation and migration, indicative of the requirement of the deubiquitinase activity."
33052017
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"In addition, several functional experiments indicated that USP21 not only promoted cell proliferation but also facilitated metastasis through regulation epithelial-mesenchymal transition (EMT) process."
28223825
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"Overexpression of USP21 promotes proliferation of BC cells."
28223825
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"XREF_FIG, ectopic USP21 expression markedly increased cell proliferation and anchorage independent growth."
29706623
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"Inhibition of USP21 in HCC cell lines decreased cell proliferation, anchorage independent growth, cell cycle progression, and in vivo tumor growth."
29706623
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"Ectopic USP21 expression promotes hepatocyte cell proliferation and tumor growth."
29706623
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"These results show that the overexpression of USP21 is sufficient to increase HCC cell proliferation in vitro and promote tumor growth in vivo."
29706623
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"Cell counting and 5-ethynyl-2 '-deoxyuridine incorporation assays reveal that USP21 promotes the proliferation of cholangiocarcinoma."
33052017
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"Since USP21 stimulated cell proliferation, migration, invasion, and stemness of GC, and could stabilize the expression of GATA3 by deubiquitinating GATA3, while MAPK1 was the transcription target of GATA3, it was further verified whether USP21 could play its oncogenic effect in GC through the GATA3 and MAPK1 axis."
33791299