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MTORC1 binds EIF3F. 2 / 2
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"They also observed that rapamycin treatment destabilizes the mTORC1 and eIF3f interaction in differentiated myotubes, and that ablation of eIF3f in muscle cells prevents mTORC1 activity and phosphorylation of S6K1, rpS6 and 4E-BP1 [XREF_BIBR]."
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"However, although sepsis does not decrease the total eIF3f protein in muscle, the amount of eIF3f bound to mTORC1 (e.g., raptor) was reduced."
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