IndraLab

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TNFAIP3 decreases the amount of TNFAIP3. 6 / 6
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"In particular, Sirt1 , Hdac4 , Arid1b , Tnfaip3 , and Pdlim2 were increased in cDC2s in response to LPS and overexpression of miR-9 did not decrease the expression of Arid1b , Tnfaip3 , and Pdlim2."
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"TNFAIP3 siRNA decreased TNFAIP3 levels compared with LPS stimulated NPCs (XREF_FIG - XREF_FIG)."
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"TNFAIP3 suppresses NF-κB activation by binding to linear ubiquitin chains via its zinc finger 7 domain (58, 59), and the SLE susceptibility SNPs of TNPAIP3 induce hypomorphic expression of TNFAIP3, which appears to augment linear ubiquitination signaling."
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"the activation of NF-κB signaling can elevate the expression of ubiquitin-editing enzyme TNFAIP3, however, the upregulated TNFAIP3 could inversely inhibit NF-κB activity."
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"The data showed that knockdown of miR-125b and TNFAIP3 could effectively increase miR-125b expression and decrease TNFAIP3 expression, while overexpression of miR-125b and TNFAIP3 could effectively re[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Firstly, we confirmed that transfection of si-TNFAIP3 markedly reduced the level of TNFAIP3 in MH7A cells."
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