IndraLab

Statements

24,25-Dihydroxyvitamin D decreases the amount of KCNH1. 2 / 2
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"For instance, calcitriol, the active metabolite of vitamin D with known antiproliferative effects, down-regulates Eag1 expression in breast tumor derived cells and in cervical cancer [XREF_BIBR, XREF_BIBR]."
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"In breast and cervical cancer cell lines vitamin D inhibited the expression of the KCNH1 oncogene, encoding voltage gated channel Eag1, and that inhibition was accompanied with a reduction in cell proliferation and decreased tumor growth [XREF_BIBR, XREF_BIBR]."
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