IndraLab

Statements

USP39 inhibits homologous recombination. 2 / 2
| 2
reach
"In addition, we also found that reintroducing either WT USP39 or the RG/AA mutant rescued USP39 depletion-mediated HR failure, but the RG/AA mutant failed to rescue the NHEJ defect caused by USP39 ablation."
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reach
"To rule out that a decrease in transcript levels of USP39-linked factors causes HR or NHEJ defects in USP39 depleted cells, we performed qPCR for USP39-linked HR or NHEJ factors and found that none of the NHEJ factors identified in this study were downregulated by USP39 depletion (Supplementary Figure S13D)."
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