IndraLab

Statements

USP9X deubiquitinates SOX2. 3 / 4
1 | 3
reach
"Usp9x knockdown in melanoma increased SOX2 ubiquitination, leading to its depletion, and enhanced apoptotic effects of BRAF inhibitor and MEK inhibitors."
33613844
reach
"Further investigation of the interaction between NGA and USP9x may provide information for optimizing more specific USP9x inhibitors.In summary, we demonstrate that USP9x can deubiquitinate and stabil[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31605775
reach
"We identified that Usp9x deubiquitinates SOX2 and can increaseSOX2 levels, but additional studies are needed to confirm the specific ubiquitin sites among the 16 lysine residues in SOX2 that could be putative ubiquitin acceptors."
33613844