IndraLab

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USP1 activates FANCI. 2 / 3
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"However, after the overexpression of SERPINB3, the expression level of USP1 was increased, which could accelerate the deubiquitination of FANCD2–FANCI during ICLs repair."
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"In addition, DUBs involved in DNA damage signaling are USP1 that targets PCNA (proliferating cell nuclear antigen) [76], FANCD2 and FANCI (the Fanconi anemia proteins) [93,94], and USP3 and USP16 that[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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