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Modified UCHL1 increases the amount of HIF1. 1 / 1
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reach
"The resultant clones, EMT6/EF-Luc/UCHL1 and EMT6/EF-Luc/EV cells, showed that the forced expression of UCHL1 induced the expression of HIF-1alpha and HIF-1 activity (XREF_SUPPLEMENTARY) and enhanced cell migration (XREF_SUPPLEMENTARY), but did not promote cell proliferation in vitro, EF-Luc reporter activity or the growth of tumour xenografts following subcutaneous transplantation (XREF_SUPPLEMENTARY)."