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Modified USP15 leads to the deubiquitination of TRIM25. 2 / 2

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"In contrast, expression of wild-type USP15, but not its catalytically inactive mutant, reduced the Lys (48)-linked ubiquitylation of TRIM25, leading to its stabilization."

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"Furthermore, ectopic expression of USP15 substantially decreased the extent of ubiquitylation of endogenous TRIM25 in virus infected cells (XREF_FIG)."

24399297

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IndraLab

Statements

Modified USP15 leads to the deubiquitination of TRIM25. 2 / 2

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