IndraLab

Statements

ZRANB1 deubiquitinates APC. 4 / 4
| 4
reach
"APC is ubiquitinated by HectD1 and RNF61 and deubiquitinated by Trabid and USP15 (Tran et al. 2008; Huang et al. 2009; Tran et al. 2013; Lee et al. 2018)."
38383910
reach
"Our data suggests that Trabid’s mechanism of action is to suppress the ubiquitylation of APC to regulate its intracellular trafficking."
38099646
reach
"For example, Trabid and Cezanne, both deubiquitinating (DUB) enzymes, antagonize the ubiquitination of APC, resulting in activation of beta-catenin and TCF-mediated transcription."
21118991
reach
"Trabid binds to and deubiquitylates APC."
24594309