IndraLab

Statements

ZRANB1 deubiquitinates APC. 4 / 4
| 4
reach
"For example, Trabid and Cezanne, both deubiquitinating (DUB) enzymes, antagonize the ubiquitination of APC, resulting in activation of beta-catenin and TCF-mediated transcription."
21118991
reach
"Trabid binds to and deubiquitylates APC."
24594309
reach
"APC is ubiquitinated by HectD1 and RNF61 and deubiquitinated by Trabid and USP15 (Tran et al. 2008; Huang et al. 2009; Tran et al. 2013; Lee et al. 2018)."
38383910
reach
"Our data suggests that Trabid’s mechanism of action is to suppress the ubiquitylation of APC to regulate its intracellular trafficking."
38099646