IndraLab

Statements

VEGFA phosphorylates PDGFRB. 4 / 5
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sparser
"PDGFB and VEGFA stimulated phosphorylation of PDGFRB and VEGFR2 in pericytes and BRAF WT/V600E -PTC, but not in BRAF WT/WT -PTC, which showed low levels of these receptors ( xref )."
30076136
reach
"Moreover, VEGF-A has been shown to negatively regulate pericyte function by inhibiting PDGFR-beta phosphorylation through the formation of a nonfunctional VEGFR-2, PDGFR, and beta complex, which results in a reduction in vascular pericyte coverage [XREF_BIBR]."
30125282
sparser
"However, VEGF-A–induced PDGFRα and PDGFRβ tyrosine phosphorylation was clearly confirmed, highlighting that VEGF-A exerts its effect on MSCs by the stimulation of PDGFRs."
17470632
reach
"As shown in XREF_FIG, the phosphorylation of PDGFRbeta by VEGFA increased with increasing concentrations."
23047550