IndraLab

Statements

UCHL1 inhibits Cell Survival. 2 / 3
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"Pharmacological inhibition of UCH-L1 farnesylation, on the other hand, was shown to reduce a-syn levels possibly by promoting its degradation through lysosomal pathway, and increased cell viability XREF_BIBR."
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"Besides its soluble form, UCHL1 also exists in a membrane associated form (UCHL1 (M)) which has been shown to correlate with intracellular levels of alpha-synuclein : decreased UCHL1 (M) reduces alpha -synuclein levels and increases cell viability."
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