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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 inhibits Cell Survival. 2 / 3

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"Pharmacological inhibition of UCH-L1 farnesylation, on the other hand, was shown to reduce a-syn levels possibly by promoting its degradation through lysosomal pathway, and increased cell viability XREF_BIBR."

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"Besides its soluble form, UCHL1 also exists in a membrane associated form (UCHL1 (M)) which has been shown to correlate with intracellular levels of alpha-synuclein : decreased UCHL1 (M) reduces alpha -synuclein levels and increases cell viability."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...